Make sauce: mix mayo, ketchup, relish, Dijon, garlic powder, onion powder, paprika. Refrigerate
Combine beef, salt, pepper, garlic powder, onion powder in bowl
Mix gently just until combined, don't overmix
Divide into 12 portions, form into thin patties slightly larger than buns
Make small indentation in center of each with thumb
Slice Hawaiian rolls in half horizontally
Heat skillet over medium-high (don't add oil)
Cook patties in batches 2-3 minutes per side until browned and 160°F internal
Add cheese slice on each during last minute, cover to melt
Transfer to plate, keep warm
Brush cut sides of buns with melted butter mixed with garlic powder
Toast in pan or under broiler 1-2 minutes until golden
Spread sauce on bottom buns, add lettuce
Place cheesy patty on lettuce
Top with tomato, pickles, onion
Spread sauce on top bun, place on slider
Secure with toothpick if desired
Serve immediately